Exemplis Discimus 2005, 149(2):243-249

Duis vel neque quis pede rhoncus vehicula.

Duena Renz, Shri-Lan Saul
Clinic of Pathology, University of Toydaria, Kashyyyk Republic

Nullam quam ante, viverra eu, cursus et, bibendum in, tortor.. Vestibulum ligula augue, auctor sollicitudin, gravida vitae, hendrerit sit amet, enim. Aliquam neque leo, rutrum nec, sagittis a, egestas in, felis. Fusce sem ligula, cursus ullamcorper, sagittis ac, egestas quis, diam. Quisque eu nulla a nulla ultrices convallis. Phasellus quis augue a quam ullamcorper posuere. Sed interdum tortor vel velit feugiat bibendum. Sed turpis metus, hendrerit nec, dictum et, accumsan ut, lacus.

Keywords: Nulla facilisi, Praesent lacinia, Cras id sem

Received: June 10, 2005; Accepted: September 25, 2005; Published: December 1, 2005 


References

  1. Weigl E, Kopeèek P, Ra¹ka M, Hradilová ©. (1999) Heat shock proteins in immune reactions. Folia Microbiologica 44, 561-6. Go to original source... Go to PubMed...
  2. Hartl FU, Hayer-Hartl M. (2002) Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 295, 1852-8. Go to original source... Go to PubMed...
  3. Mathew A, Mathur SK, Morimoto RI. (1998) Heat Shock Response and Protein Degradation: Regulation of Hsf2 by the Ubiquitin- Proteasome Pathway. Mol Cell Biol 18, 5091-8. Go to PubMed...
  4. Berwin B, Nicchitta CV. (2001) To find the road traveled to tumor immunity: the trafficking itineraries of molecular chaperones in antigen-presenting cells. Traffic 2, 690-7. Go to original source... Go to PubMed...
  5. Vambutas A, DeVoti J, Pinn W, Steinberg BM, Bonagura VR. (2001) Interaction of human papillomavirus type 11 e7 protein with tap-1 results in the reduction of atp-dependent peptide transport. Clin Immunol 101, 94-9. Go to original source... Go to PubMed...
  6. Murphy-Ullrich JE. (2001) The de-adhesive activity of matricellular proteins: is intermediate cell adhesion an adaptive state? J Clin Invest 107, 785-90. Go to original source... Go to PubMed...
  7. Rutherford SL, Lindquist S. (1998) Hsp90 As a Capacitor For Morphological Evolution. Nature 396, 336-42. Go to original source... Go to PubMed...
  8. Ohashi K, Burkart V, Flohe S, Kolb H. (2001) Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 164, 558-61. Go to original source... Go to PubMed...
  9. Basu S, Binder RJ, Ramalingam T, Srivastava PK. (2001) CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin. Immunity 14, 303-13. Go to original source... Go to PubMed...
  10. Srivastava PK, Jaikaria NS. (2001) Methods of purification of heat shock protein-peptide complexes for use as vaccines against cancers and infectious diseases. Methods Mol Biol 156, 175-86. Go to PubMed...
  11. Quintana FJ, Cohen IR. (2005) Heat shock proteins as endogenous adjuvants in sterile and septic inflammation. J Immunol 175, 2777-82. Go to original source... Go to PubMed...
  12. van Eden W, van der Zee R, Prakken B. (2005) Heat-shock proteins induce T-cell regulation of chronic inflammation. Nat Rev Immunol 5, 318-30. Go to original source... Go to PubMed...
  13. OBrien RL, Fu YX, Cranfill R, Dallas A, Ellis C, Reardon C, Lang J, Carding SR, Kubo R, Born W. (1992) Heat shock protein hsp60-reactive gamma/delta cells. A large, diversified T-lymphocyte subset with highly focused specificity. Proc Natl Acad Sci USA 89, 4348-52. Go to original source... Go to PubMed...
  14. Born W, Hall L, Dallas A, Boymel J, Shinnick T, Young D, Brehnan P, OBrien RL. (1990) Recognition of a peptide antigen by heat shock reactive gamma/delta T lymphocytes. Science 249, 67-9. Go to original source... Go to PubMed...
  15. Himeno K, Hisaeda H. (1996) Contribution of 65-kDa heat shock protein induced by gamma delta T cells to protection against Toxoplasma gondii infection. Immunol Res 15, 258-64. Go to original source... Go to PubMed...
  16. Hansen K, Bangsborg JM, Fjordvang H, Pedersen NS, Hindersson P. (1988) Immunochemical characterization of, and isolation of the gene for Borrelia burgdorferi immunodominant 60-kilodalton antigen common to a wide range of bacteria. Infect Immun 56, 2047-53. Go to PubMed...
  17. Danilition SL, Maclean IW, Peeling R, Winston S, Brunham RC. (1990) The 75-kilodalton protein of Chlamydia trachomatis: a member of the heat shock protein 70 family. Infect. Immun 58, 189-96. Go to PubMed...
  18. Morrison RP, Belland RJ, Lyng K, Caldwell HD. (1989) Chlamydial disease pathogenesis. The 57-kD chlamydial hypersensitivity antigen is a stress response protein. J Exp Med 170, 1271-83. Go to original source... Go to PubMed...
  19. Ferrero RL, Thilberge JM, Kansau I, Wuscher N, Huerre M, Labigne A. (1995) The GroES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice. Proc Natl Acad Sci USA 92, 6499-503. Go to original source... Go to PubMed...
  20. Yamakoshi M, Taguchi H, Yoshida M. A Chaperonin from Thermophilic Bacterium Thermus thermopilus. In: AF Fink, Y Goto (Eds). Molecular Chaperones in the Life Cycle of Proteins Marcel Dekker Inc, New York 1998. p. 301-2.
  21. Garsia RJ, Hellqvist L, Booth RJ, Radford AJ, Britton WJ, Astbury L, Trent RJ, Basten A. (1989) Homology of the 70-kilodalton antigens from Mycobacterium leprae and Mycobacterium tuberculosis 71-kilodalton antigen and with the conserved heat shock protein 70 of eucaryotes. Infect Immun 57, 204-12. Go to PubMed...
  22. Bonato VLD, Lima VMF, Tascon RE, Lowrie DB, Silva CL. (1998) Identification and Characterization of Protective T Cells in hsp65 DNA-Vaccinated and Mycobacterium tuberculosis-Infected Mice. Infect Immun 66, 169-75. Go to PubMed...
  23. Noll A, Rogenkamp A, Heesemann J, Autenrieth IB. (1994) Protective role for heat shock protein-reactive ab T cells in murine yersiniosis. Infect Immun 62, 2784-91. Go to PubMed...
  24. Jendoubi M, Bonnefoy S. (1988) Identification of a heat shock-like antigen in P. falciparum, related to the heat shock protein 90 family. Nucleic Acids Res. 16, 10928-31. Go to original source... Go to PubMed...
  25. Raska M, Rybnikar A, Chumela J, Belakova J, Weigl E. (2004) Recombinant protein and DNA vaccines derived from hsp60 protein Trichophyton mentagrophytes control the clinical course of trichophytosis in bovine species and guinea pigs. Mycoses 47, 407-17. Go to original source... Go to PubMed...
  26. Raska M, Belakova J, Wudattu NK, Kafkova L, Ruzickova K, Kolar Z, Weigl E. (2005) Comparison of protective effect of protein and DNA vaccines hsp90 in murine model of systemic candidiasis. Folia Microbiologica 50, 77-82. Go to original source... Go to PubMed...
  27. Zûgel U, Kaufmann SHE. (1997) Activation of CD8 T cells with specificity for mycobacterial heat shock protein 60 in Mycobacterium bovis bacillus Calmette-Guerin-vaccinated mice. Infect Immun 65, 3947-50. Go to PubMed...
  28. Zûgel U, Kaufmann SHE. (1999) Role of Heat Shock Proteins in Protection from and Pathogenesis of Infectious Diseases. Clin Microb Rev 12, 19-39.
  29. Steinhoff U, Zügel U, Hengel H, Rösch R, Munk ME, Kaufmann SHE. (1994) Prevention of autoimmune lysis by T cells with specificity for a heat shock protein by anti-sense oligonucleotide treatment. Proc Natl Acad Sci USA 91, 5085-8. Go to original source... Go to PubMed...
  30. Billingham MEJ, Carney S, Butler R, Collston MJ. (1990) A mycobacterial heat shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritogenic. J Exp Med 171, 339-44. Go to original source... Go to PubMed...
  31. Thompson SJ, Rook GAW, Brealey RJ, van der Zee R, Elson CJ. (1990) Autoimmune reactions to heat-shock proteins in pristaneinduced arthritis. Eur J Immunol 20, 2479-84. Go to original source... Go to PubMed...
  32. van den Broek MF, Hagervorst EJM, van Bruggen MCJ, van Eden W, van der Zee R, van den Berg WB. (1989) Protection against streptococcal cell wall-induced arthritis by pretreatment with the 65-kD mycobacterial heat shock protein. J Exp Med 170, 449- 66. Go to original source... Go to PubMed...
  33. Elias D, Markovits D, Reshef T, van der Zee R, Cohen IR. (1990) Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein. Proc Natl Acad Sci USA 87, 1576-80. Go to original source... Go to PubMed...
  34. Shimada A, Kasatani T, Takei I, Maruyma T, Nomaguchi H, Ozawa Y, Ishii M, Kasuga A, Tashiro F, Miyazaki J, Yamamura K, Saruta T. (1996) Immune response to heat-shock protein correlates with induction of insulitis in I-E alpha transgenic NOD mice. Diabetes 45, 165-9. Go to original source... Go to PubMed...
  35. Pearson CM. (1956) Development of arthritis, periarthritis and periostitis in rats giving adjuvant. Proc Soc Exp Biol Med 91, 95-101. Go to original source... Go to PubMed...
  36. van Eden W, Hauet-Broere F, Berlo S, Paul L, van der Zee R, de Kleer I, Prakken B, Taams L. (2005) Stress proteins as inducers and targets of regulatory T cells in arthritis. Int Rev Immunol 24, 181-97. Go to original source... Go to PubMed...
  37. van Eden W, Wendling U, Paul L, Prakken B, van Kooten P, van der Zee R. (2000) Arthritis protective regulatory potential of selfheat shock protein cross-reactive T cells. Cell Stress Chaperones 5, 452-7. Go to original source... Go to PubMed...
  38. Raz I, Eldor R, Naparstek Y. (2005) Immune modulation for prevention of type 1 diabetes mellitus. Trends in Biotechnology 23, 128-34. Go to original source... Go to PubMed...
  39. Raz I, Elias D, Avron A, Tamir M, Metzger M, Cohen IR. (2001) -cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277). a randomised, double-blind, phase II trial. Lancet 358, 1749-53. Go to original source... Go to PubMed...
  40. Waksman BH. (2002) Immune regulation in adjuvant disease and other arthritis models: relevance to pathogenesis of chronic arthritis. Scand J Immunol 56, 12-34. Go to original source... Go to PubMed...
  41. van Eden W, Waksman BH. (2003) Immune Regulation in Adjuvant-Induced Arthritis Possible Implications for Innovative Therapeutic Strategies in Arthritis. Artritis Rheumatism 48, 1788- 1796. Go to original source...
  42. Cohen IR, Holoshitz J, van Eden W, Frenkel A. (1985) T lymphocyte clones illuminate pathogenesis and affect therapy of experimental arthritis. Arthritis Rheum 28, 841-5. Go to original source... Go to PubMed...
  43. van Bilsen JH, Wagenaar-Hilbers JP, Boot EP, van Eden W, Wauben MH. (2002) Searching for the cartilage-associated mimicry epitope in adjuvant arthritis. Autoimmunity 35, 201. Go to original source... Go to PubMed...
  44. Beech JT, Siew LK, Ghoraishian M, Stasiuk LM, Elson CJ, Thompson SJ. (1997) CD4+ T cells specific for mycobacterial 65-kilodalton heat shock protein protect against pristane induced arthritis. J Immunol 159, 3692-7. Go to PubMed...
  45. Bendele A, Sennello G, McAbee T. (1999) Effects of interleukin 1 receptor antagonist alone and in combination with methotrexate in adjuvant arthritic rats. J Rheumatol 26, 1225. Go to PubMed...
  46. Paul AGA, van Kooten PJS, van Eden W, van der Zee R. (2000) Highly Autoproliferative T Cell Specific for 60 kDa Heat Shock Protein Produce IL-4/IL-10, IFN-gamma and Are Protective in Adjuvant Arthritis. J Immunol 165, 7270-7. Go to original source... Go to PubMed...
  47. Paul AGA,van der Zee R,Taams LS, van Eden W. (2000) Aselfhsp60 peptide acts as a partial agonist inducing expression of B7-2 on mycobacterial hsp60-specific T cells: a possible mechanism for inhibitory T cell regulation of adjuvant arthritis? Int Immunol 12, 1041-50. Go to original source... Go to PubMed...
  48. Krummel MF, Allison JP. (1995) CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med 182, 459-65. Go to original source... Go to PubMed...
  49. Kingston AE, Hicks CA, Colston MJ, Billingham ME. (1996) A 71- kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis. Clin Exp Immunol 103, 77-82. Go to original source... Go to PubMed...
  50. Tanaka S. (1999) Activation of T cells recognizing an epitope of heatshock protein 70 can protect against rat adjuvant arthritis. J Immunol 163, 5560-5. Go to PubMed...
  51. Quintana FJ, Carmi P, Mor F, Cohen IR. (2004) Inhibition of adjuvant-induced arthritis by DNA vaccination with the 70-kd or the 90-kd human heat-shock protein. immune cross-regulation with the 60-kd heat-shock protein. Arthritis Rheum 50, 3712-20. Go to original source... Go to PubMed...
  52. Quintana FJ, Cohen IR. (2005) DNA vaccines coding for heatshock proteins (HSPs). tools for the activation of HSP-specific regulatory T cells. Expert Opin Biol Ther 5, 545-54. Go to original source... Go to PubMed...
  53. Wendling U, Paul L, van der Zee R, Prakken B, Singh M, van Eden W. (2000) A conserved mycobacterial heat shock protein (hsp) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL10-producing T cells that cross-react with the mammalian self-hsp70 homologue. J Immunol 164, 2711-7. Go to original source... Go to PubMed...
  54. Bras A, Aguas AP. (1996) Diabetes-prone NOD mice are resistant to Mycobacterium avium and the infection prevents autoimmune disease. Immunology 89, 20-5. Go to original source... Go to PubMed...
  55. Elias D, Reshef T, Birk OS, van der Zee R, Walker MD, Cohen IR. (1991) Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein. Proc Natl Acad Sci USA 88, 3088-91. Go to original source... Go to PubMed...
  56. Brudzynski K, Martinez V, Gupta RS. (1992) Immunocytochemical localization of heat-shock protein 60-related protein in beta-cell secretory granules and its altered distribution in non-obese diabetic mice. Diabetologia 35, 316-24. Go to original source... Go to PubMed...
  57. Brudzynski K, Martinez V, Gupta RS. (1992) Secretory granule autoantigen in insulin-dependent diabetes mellitus is related to the 62 kDa heat-shock protein (hsp60). J Autoimmun 5, 453-63. Go to original source... Go to PubMed...
  58. Elias D, Meilin A, Ablamunits V, Birk OS, Carmi P, Koenen- Waisman S, Cohen IR. (1997) Hsp60 peptides therapy of NOD mouse diabetes induces a Th2 cytokine burst and downregulates autoimmunity to various beta-cell antigens. Diabetes 46, 758-64. Go to original source... Go to PubMed...
  59. Jiao X, Lo-Man R, Winter N, Deriaud E, Gicquel B, Leclerc C. (2003) The shift of Th1 to Th2 Immunodominance Associated with the Chronicity of Mycobacterium bovis Bacille Calmette-Guerin Infection Does Not Affect the Memory Response. J Immunol 170, 1392-8. Go to original source... Go to PubMed...
  60. Atkinson MA, Kaufman DL, Campbell L, Gibbs KA, Shah SC, Bu DF, Erlander MG, Tobin AJ, MacIaren NK. (1992) Response of peripheral-blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes. Lancet 339, 458-9. Go to original source... Go to PubMed...
  61. Tisch R, Yang X-D, Singer SM, Liblau RS, Fugger L, McDevitt HO. (1993) Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature 366, 72-5. Go to original source... Go to PubMed...
  62. Zechel MA, Elliott JF, Atkinson MA, Singh B. (1998) Charac terization of novel T-cell epitopes on 65 kDa and 67 kDa glutamic acid decarboxylase relevant in autoimmune responses in NOD mice. J Autoimmun 11, 83-95. Go to original source... Go to PubMed...
  63. Tian C, Bagley J, Cretin N, Seth N, Wucherpfennig KW, Iacomini J. (2004) Prevention of type 1 diabetes by gene therapy. J Clin Invest 114, 969-78. Go to original source... Go to PubMed...
  64. Multhoff G, Botzler C, Jennen L, Schmidt J, Ellwart J, Issels R. (1997) Heat shock protein 72 on tumor cells. a recognition structure for natural killer cells. J Immunol 158, 4341-50. Go to PubMed...
  65. Shanafelt MC, Hindersson P, Soderberg C, Mensi N, Turck CW, Webb D, Yssel H, Peltz G. (1991) T cell and antibody reactivity with the Borrelia burgdorferi 60-kDa heat shock protein in lyme arthritis. J Immunol 146, 3985-92. Go to PubMed...
  66. Kleindienst R, Xu Q, Willeit J, Waldenberger FR, Weimann S, Wick G. (1993) Immunology of atherosclerosis. Demonstration of heat shock protein 60 expression and T lymphocytes bearing alpha/beta or gamma/delta receptor in human atherosclerotic lesions. Am J Pathol 142, 1927-37. Go to PubMed...
  67. Shimonkevitz R, Colburn C, Burnham JA, Murray RS, Kotzin BL. (1993) Clonal expansion of activated gamma/delta T cells in recentonset multiple sclerosis. Proc Natl Acad Sci USA 90, 923-7. Go to original source... Go to PubMed...
  68. Freedman MS, Buu NN, Ruijs TC, Williams K, Antel JP. (1992) Differential expression of heat shock proteins by human glial cells. J Neuroimmunol 41, 231-8. Go to original source... Go to PubMed...
  69. Peetermans WE. Expression of and immune response to heat shock protein 65 in Crohns disease. In: van Eden W, Young DB, editors. Stress proteins in medicine. Marcel Dekker Inc, New York 1996. p. 197-1.
  70. Mattei D, Ozaki LS, Pereira da Silva L. (1988) A Plasmodium falciparum gene encoding a heat shock-like antigen related to the rat 78 kD glucose-regulated protein. Nucleic Acids Res 16, 5204-8 Go to original source... Go to PubMed...
  71. Erkeller-Yueksel FM, Isenberg DA, Dhillon VB, Latchman DS, Lydyard PM. (1992) Surface expression of heat shock protein 90 by blood mononuclear cells from patients with systemic lupus erythematosus. J Autoimmun 5, 803-14. Go to original source... Go to PubMed...
  72. Faulds GB, Isenberg DA, Latchman DS. (1994) The tissue-specific elevation in synthesis of 90 kD-heat shock protein precedes the onset of disease in lupus-prone MRL/lpr mice. J Rheumatol 21, 234-8. Go to PubMed...
  73. Kaufmann SHE, Schoel B. Heat shock proteins as antigens in immunity against infection and self. In: Morimoto RI, Tissieres A, Georgopoulos C, editors. The biology of heat shock proteins and molecular chaperones. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, 1994. p. 495-531.
  74. Wills-Karp M, Santeliz J, Karp CL. (2001) The germless theory of allergic disease: revisiting the hygiene hypothesis. Nat Rev Immunol 1, 69-75. Go to original source... Go to PubMed...
  75. Weiner HL. (2000) Oral tolerance, an active immunologic process mediated by multiple mechanisms. J Clin Invest 106, 935-7. Go to original source... Go to PubMed...
  76. Cobelens PM, Heijnen CJ, Nieuwenhuis EES, Kramer PPG, van der Zee R, van Eden W, Kavelaars A. (2000) Treatment of adjuvant- induced arthritis by oral administration of mycobacterial hsp65 during disease. Arthritis Rheum 43, 2694-702. Go to original source... Go to PubMed...
  77. Harats D, Yacov N, Gilburd B, Shoenfeld Y, George J. (2002) Oral tolerance with heat shock protein 65 attenuates Mycobacterium tuberculosis-induced and high-fat-diet-driven atherosclerotic lesions. J Am Coll Cardiol 40, 1333-8. Go to original source... Go to PubMed...
  78. Maron R, Sukhova G, Faria AM, Hoffmann E, Mach F, Libby P, Weiner HL. (2002) Mucosal administration of heat shock protein- 65 decreases atherosclerosis and inflammation in the aortic arch of low-density lipoprotein receptor-deficient mice. Circulation 106, 1708-15. Go to original source... Go to PubMed...
  79. Kweon MN, Kiyono H. (2002) CD40L in autoimmunity and mucosally induced tolerance. J Clin Invest 109, 171-3. Go to original source... Go to PubMed...
  80. Jardetzky TS, Lane WS, Robinson RA, Madden DR, Wiley DC. (1991) Identification of self peptides bound to purified HLA-B27. Nature 353, 326-9. Go to original source... Go to PubMed...
  81. Anderton SM, van der Zee R, Goodacre JA (1993) Inflammation activates self hsp60-specific T cells. Eur J Immunol 23, 33-8. Go to original source... Go to PubMed...
  82. E, Lohse AW, van der Zee R, van Eden W, Mayet W, Probst P, Poralla T, Meyer zum Buschenfelde KM, Fleischer B. (1991) Synovial fluid-derived Yersinia-reactive T cells responding to human 65-kDa heat-shock protein and heat-stressed antigen-presenting cells. Eur J Immunol 21, 2139-43. Go to original source... Go to PubMed...
  83. Lehner T, Childerstone A, Pervin K, Hasan A, Direskeneli H, Stanford MR, Whiston R, Kasp E, Dumonde DC, Shinnick T, van der Zee R, Mizushima Y. Stress proteins in Bechets disease and experimental uveitis. In: van Eden W, Young DB, editors. Stress proteins in medicine. Marcel Dekker Inc, New York 1996. p. 163- 83.
  84. Pervin K, Childerstone A, Shinnick T, Mizushima Y, van der Zee R, Hasan A, Vaughan R, Lehner T. (1993) T cell epitope expression of mycobacterial and homologous human 65-kilodalton heat shock protein peptides in short term cell lines from patients with Behcets disease. J Immunol 151, 2273-82. Go to PubMed...
  85. Li SG, Quayle AJ, Shen Y, Kjeldsen-Kragh J, Oftung F, Gupta RS, Natvig JB, Forre OT. (1992) Mycobacteria and human heat shock protein-specific cytotoxic T lymphocytes in rheumatoid synovial inflammation. Arthritis Rheum 35, 270-81. Go to original source... Go to PubMed...
  86. De Graeff-Meeder ER, van der Zee R, Rijkers GT, Schuurman HJ, Kuis W, Bijlsma JWJ, Zegers BJM, van Eden W. (1991) Recognition of human 60 kD heat shock protein by mononuclear cells from patients with juvenile chronic arthritis. Lancet 337, 1368-72. Go to original source... Go to PubMed...
  87. Gaston JSH. (1997) Heat Shock Proteins and Arthritis - New Readers Start Here. Autoimmuity 26, 33-42. Go to original source... Go to PubMed...
  88. Fu YX, Kersh G, Vollmer M, Kalataradi H, Heyborne K, Reardon C, Miles C, OBrien RL, Born W. (1994) Structural requirements for peptides that stimulate a subset of gamma/delta T cells. J Immunol 152, 1578-88. Go to PubMed...
  89. Cho BK, Palliser D, Guillen E, Wisniewski J, Young RA, Chen J, Eisen HN. (2000) A proposed mechanism for the induction of cytotoxic T lymphocyte production by heat shock fusion proteins. Immunity 12, 263-72. Go to original source... Go to PubMed...