Exemplis Discimus 2008, 152(1):27-33

Donec nunc nibh, cursus ac, ultricies vel, malesuada ut, turpis.

Katara Securaa, Sealeen Nuruodoa, Keenor Nostb, Victor Solimara
a 1st Clinic of Oral and Maxillofacial Surgery, Teaching Hospital of Hoth, Ansion Republic
b Clinic of Epidemiology and Biostatistics, Juvex Faculty Hospital, Republic of Yavin

Background: Praesent vitae sem pellentesque ante porta aliquam. Donec sit amet sapien vel nunc malesuada rhoncus. Suspendisse fringilla sapien et ante tempor scelerisque. Suspendisse orci lorem, porttitor quis, accumsan eget, vestibulum eget, elit. Sed magna felis, viverra in, pharetra at, sodales eu, ante. Suspendisse pede lectus, iaculis id, pharetra et, porta non, leo. Nulla tellus sapien, adipiscing adipiscing, aliquet ac, elementum ac, nunc. Nunc ac tortor eget lorem condimentum imperdiet.

Methods and Results: Morbi in nisl. Donec nec tellus.

Conclusion: Vivamus neque eros, tristique eu, lobortis sit amet, volutpat id, sem. Donec sed diam tincidunt augue tempus adipiscing. Nullam nisi enim, feugiat in, pulvinar et, cursus ut, ante. Curabitur vitae velit accumsan pede accumsan vehicula. Donec felis pede, vestibulum sagittis, blandit eu, faucibus non, lectus. Sed dolor est, porttitor ac, tempor ac, sagittis et, arcu. Proin nulla diam, commodo ac, cursus quis, ullamcorper et, diam. Curabitur dui orci, suscipit nec, pulvinar id, auctor blandit, velit.

Kľúčové slová: Sed sed est, Donec augue, Quisque molestie, Suspendisse potenti, Nunc risus, Praesent ipsum, Nam sollicitudin, Integer feugiat

Vložený: November 30, 2007; Přijatý: January 18, 2008; Uverejnené: June 1, 2008 


Referencie

  1. Bolanos-Garcia M. Aurora Kinases. Int. J. Biochem. & Cell Biol. 2004; 37:1572-7.
  2. Carmena M, Earnshaw WC. The Cellular Geography of Aurora Kinases. Nat. Rev. Mol. Cell. Biol. 2003; 4:842-54. Prejsť k pôvodnému zdroju...
  3. Brown JR, Koretke KK, Birkeland ML, Sanseau P, Patrick DR. Evolutionary relationships of Aurora kinases: Implications for model organism studies and the development of anti-cancer drugs. BMC Evol. Biol. 2004; 4:1-10. Prejsť k pôvodnému zdroju...
  4. Cheetam GMT, Knegtel RMA, Coll JT, Renwick SB, Swenson L, Weber P, Lippke, JA, Austen DA. Crystal Structure of Aurora- 2, an Oncogenic Serine/Threonine Kinase. J. Biol. Chem. 2000; 277:42419-22. Prejsť k pôvodnému zdroju...
  5. Bischoff JR, Anderson L, Zhu Y, Mossie K, Ng L, Souza B, Schryver B, Flanagan P, Clairvoyant F, Ginther C, Chan CS, Novotny M, Slamon DJ, Plowman GD. A Homologue of Drosophila Aurora kinase is Oncogenic and amplifi ed in human colorectal cancers. EMBO J. 1998; 17:3052-65. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  6. Kimura M, Matsuda Y, Yoshioka T, Sumi N, Okano Y. Identifi cation and characterization of STK12/Aik2: a human gene related to aurora of Drosophila and yeast IPL1. Cytogenet. Cell Genet. 1998; 82:147-52. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  7. Bernard M, Sanseau P, Henry C, Couturier A, Prigent C. Cloning of STK13, a third human protein kinase related to Drosophila aurora and budding yeast Ipl1 that maps on chromosome 19q13.3-ter. Genomics 1998; 53:4069. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  8. Adams RR. Carmena M, Earnshaw WC. Chromosomal passengers and the (aurora) ABCs of mitosis. Trends Cell Biol. 2001; 1:49- 54. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  9. Kimura M, Matsuda Y, Yoshioka T, Okano Y. Cell cycle-dependent expression and centrosome localization of a third human Aurora/ Ipl1-related protein kinase, AIK3. J. Biochem. 1999; 274:7334- 40.
  10. Eyers PA, Erikson E, Chen LG, Maller JL. A novel mechanism for activation of the protein kinase Aurora A. Curr. Biol. 2003; 13:6917. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  11. Hirota T, Kunitoku N, Sasayama T, Marumoto T, Zhang D, Nitta M, Hatakeyama K, Saya H. Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell 2003; 114:58598. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  12. Giet R, Uzbekov R, Cubizolles F, Le Guellec K, Prigent C. The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XlEg5. J. Biol. Chem. 1999; 274:15005 13. Prejsť k pôvodnému zdroju...
  13. Dutertre S, Cazales M, Quaranta M, Froment C, Trabut V, Dozier C, Mirey G, Bouché JP, Theis-Febvre N, Schmitt E, Monsarrat B, Prigent C, Ducommun B. Phosphorylation of CDC25B by Aurora- A at the centrosome contributes to the G2-M transition. J. Cell. Sci. 2004; 117:252331. Prejsť k pôvodnému zdroju...
  14. Liu Q, Kaneko S, Yang L, Feldman RI, Nicosia SV, Chen J, Cheng JQ. Aurora-A Abrogation of p53 DNA binding and transactivation activity by phosphorylation of serine 215. J. Biol. Chem. 2004; 279:5217582. Prejsť k pôvodnému zdroju...
  15. Ouchi M, Fujiuchi N, Sasai K, Katayama H, Minamishima YA, Ongusaha PP, Deng C, Sen S, Lee SW, Ouchi T. BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition. J. Biol. Chem. 2004; 279:196438. Prejsť k pôvodnému zdroju...
  16. Goto H, Yasui Y, Nigg EA, Inagaki M. Aurora B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation. Genes Cells 2002; 7:11-7. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  17. Knowlton AL, Lan W, Stukenberg P. Aurora B is enriched at merotelic attachment sites, where it regulated MCAK. Curr. Biol. 2006; 16:1705-10. Prejsť k pôvodnému zdroju...
  18. Brittle AL, Nanba Y, Ito T, Ohkura H. Concerted action of Aurora B, Polo and NHK-1 kinases in centromere-specifi c histone 2A phosphorylation. Exp. Cell Res. 2007; 313:2780-5. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  19. Morrison C, Henzing AJ, Jensen ON, Osheroff N, Dodson H, Kandels-Lewis SE, Adams RR, Earnshaw WC. Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate. Nucleic Acids Res. 2002; 30:5318-27. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  20. Speliotes EK, Uren A, Vaux D, Horvitz HR. The survivin-like C. elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to aff ect chromosomes and the spindle midzone. Mol. Cell 2000; 6:211- 23. Prejsť k pôvodnému zdroju...
  21. Zeitlin SG, Shelby RD, Sullivan KF. CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis. J. Cell Biol. 2001; 155:114757. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  22. Li X, Sakashita G, Matsuzaki H, Sugimoto K, Kimura K, Hanaoka F, Taniguchi H, Furukawa K, Urano T. Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C. J. Biol. Chem. 2004; 279:4720111. Prejsť k pôvodnému zdroju...
  23. Marumoto T, Honda S, Hara T, Nitta M, Hirota T, Kohmura E, Saya H. Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic events in HeLa Cells. J. Biol. Chem. 2003; 278:51786-95. Prejsť k pôvodnému zdroju...
  24. Berdnik D, Knoblich, JA. Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Curr. Biol. 2002; 12:6407. Prejsť k pôvodnému zdroju...
  25. Hannak E, Kirkham M, Hyman AA, Oegema K. Aurora-A kinase is required for centrosome maturation in Caenorhabditis elegans. J. Cell Biol. 2001; 155:110916. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  26. Kemp CA, Kopish KR, Zipperlen P, Ahringer J, O'Connell KF. Centrosome maturation and duplication in C. elegans require the coiled-coil protein SPD-2. Dev. Cell 2004; 6:51123. Prejsť k pôvodnému zdroju...
  27. Conte N, Delaval B, Ginestier C, Ferrand A, Isnardon D, Larroque C, Prigent C, Séraphin B, Jacquemier J, Birnbaum D. TACC1chTOGAurora A protein complex in breast cancer. Oncogene 2003; 22:8102-16. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  28. Portier N, Audhya A, Maddox PS, Green RA, Dammermann A, Desai A, Oegema K. A microtubule-independent role for centrosomes and Aurora A in nuclear envelope breakdown. Dev. Cell 2007; 12:515-29. Prejsť k pôvodnému zdroju...
  29. Adams RR, Maiato H, Earnshaw WC, Carmena M. Essential Roles of Drosophila Inner Centromere Protein (INCENP) and Aurora B in Histone H3 Phosphorylation, Metaphase Chromosome Alignment, Kinetochore Disjunction, and Chromosome Segregation. J. Biol. Chem. 2001; 15:865-80.
  30. Hauf S, Cole RW, LaTerra S, Zimmer C, Schnapp G, Walter R, Heckel A, van Meel J, Rieder CL, Peters JM. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore microtubule attachment and in maintaining the spindle assembly checkpoint. J.Biol.Chem. 2003; 16:281-94.
  31. Littlepage LE, Wu H, Andresson T, Deanehan JK, Amundadottir LT, Ruderman JV. Identifi cation of phosphorylated residues that aff ect the activity of the mitotic kinase Aurora A. Proc. Natl. Acad. Sci. U.S.A. 2002; 99:15440-5. Prejsť k pôvodnému zdroju...
  32. Walter AO, Seghezzi W, Korver W, Sheung J, Lees E. The mitotic serine/threonine kinase Aurora 2/AIK is regulated by phosphorylation and degradation. Oncogene 2000; 19:4906-16. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  33. Honda K, Mihara H, Kato Y, Yamaguchi A, Tanaka H, Yasuda H, Furukawa K, Urano T. Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway. Oncogene 2000; 19:2812-9. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  34. Castro A, Arlot-Bonnemains Y, Vigneron S, Jean-Claude L, Prigent C, Lorca T. APC/Fizzy-Related targets Aurora-A kinase for proteolysis. EMBO Rep. 2002; 3:457-62. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  35. Zachos G, Black E, Walker M, Scott M, Vagnarelli P, Earnshaw W. Chk1 is required for spindle checkpoint fucntion. Dev. Cell 2007; 12:247-60. Prejsť k pôvodnému zdroju...
  36. Chen J, Jin S, Tahir SK, Zhang H, Liu X, Sarthy AV, McGonigal TP, Liu Z, Rosenberg SH, Ng SC. Survivin enhances Aurora-B kinase activity and localizes Aurora B in human cells. J. Biochem. 2003; 278:486-90.
  37. Honda R, Korner R, Nigg EA. Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Mol. Biol. Cell 2003; 14:3325-41. Prejsť k pôvodnému zdroju...
  38. Nguyen HG, Chinnappan D, Urano T, Ravid K. Mechanism of Aurora-B Degradation and Its Dependency on Intact KEN and ABoxes: Identifi cation of an Aneuploidy-promoting Property. Mol. Cell. Biol. 2005; 25:4977-92. Prejsť k pôvodnému zdroju...
  39. Sasai K, Katayama H, Stenoien DL, Fujii S, Honda R, Kimura M, Okano Y, Tatsuka M, Suzuki F, Nigg EA, Earnshaw WC, Brinkley WR, Sen S. Aurora-C is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motil. Cytoskeleton 2004; 59:249-63. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  40. Sen S, Zhou H, White RA. A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplifi ed and overexpressed in human breast cancer cell lines. Oncogene 1997; 14:2195200. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  41. Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW, Sahin A, Brinkley BR, Sen S. Tumour amplifi ed kinase STK15/BTAK induces centrosome amplifi cation, aneuploidy and transformation. Nat. Genet. 1998; 20:189-93. Prejsť k pôvodnému zdroju...
  42. Tchatchou S, Wirtenberger M, Hemminki K, Sutter C, Meindl A, Wappenschmidt B, Kiechle M, Bugert P, Schmutzler RK, Bartram CR, Burwinkel B. Aurora kinases A and B and familial breast cancer risk. Cancer Lett. 2007; 247:266-72. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  43. Gu J, Gong Y, Huang M, Lu C, Spitz MR, Wu X. Polymorphisms of STK15 (Aurora-A) gene and lung cancer risk in Caucasians. Carcinogenesis 2007; 28:350-5. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  44. Katayama H, Ota T, Jisaki F, Ueda Y, Tanaka T, Odashima S, Suzuki F, Terada Y, Tatsuka M. Mitotic kinase expression and colorectal cancer progression. J. Natl. Cancer Inst. 1999; 91: 1160-2. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  45. Sorrentino R, Libertini S, Pallante PL, Troncone G, Palombini L, Bavetsias V, Spalletti-cernia D, Laccetti P, Linardopoulos S, Chieffi P, Fusco A, Portell G. Aurora B overexpression associates with the thyroid carcinoma undiff erentiated phenotype and is required for thyroid carcinoma cell proliferation. J. Clin. Endocrinol. Metab. 2004; 90:92835. Prejsť k pôvodnému zdroju...
  46. Guangying Q, Ikuko O, Yasusei K, Mutsumi M, Siriwardena B, Fumio S, Masaaki M, Takashi A. Aurora-B overexpression and its correlation with cell proliferation and metastasis in oral cancer. Springer 2007; 450:297-302.
  47. Smith SL, Bowers NL, Betticher DC, Gautschi O, Ratschiller D, Hoban PR, Booton R, Santibáńez-Koref MF, Heighway J. Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability. Br. J. of cancer 2005; 93:719-29. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  48. Reichardt W, Jung V, Brunner C, Klein A, Wemmert S, Romeike BFM, Zang KD, Urbschat S. The putative serine/threonine kinase gene STK15 on chromosome 20q13.2 is amplifi ed in human gliomas. Oncol. Rep. 2003; 10:1275-9. Prejsť k pôvodnému zdroju...
  49. Buschhorn HM, Klein RR, Chambers SM, Hardy MC, Green S, Bearss D, Nagle RB. Aurora-A over-expression in high-grade PIN lesions and prostate cancer. The Prostrate 2005; 64:341-6. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  50. Li D, Zhu J, Firozi PF, Abbruzzese JL, Evans DB, Cleary K, Friess H, Sen S. Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer. Clin. Cancer Res. 2003; 9:991-7. Prejsť na PubMed...