Exemplis Discimus 2013, 157(2):153-161

Nunc ac tortor eget lorem condimentum imperdiet.

Koon Glopioa, Ru Baruba Agnetab, Shinnan Sekia, Jarvis Wanc, Rhea Mefrida, Keenor Lassiterf, Rek Aneze, Vivi Lassicd, Sam Obdrisa, Sylvain Athana
a Clinic of Urology, Faculty Hospital of Subterrel, Hoth Republic
b 2nd Clinic of Plastic surgery, Kalee University Hospital, Republic of Hoth
c Centre of Endodontics, Nal Hutta University Hospital, Republic of Cato Neimoidia
d Faculty of Biophysics, Mayagil Faculty Hospital, Republic of Boz Pity
e 2nd Clinic of Orthopaedics, University of Subterrel, Republic of Kessel
f Laboratory of Management Sciences and Health Economics, Dathomir University Hospital, Republic of Utapau

Aim: Sed tincidunt, erat vitae egestas consequat, diam enim dapibus leo, in accumsan dui orci a quam. Vestibulum ante ipsum primis in faucibus orci luctus et ultrices posuere cubilia Curae; Praesent pede sapien, malesuada a, sodales non, cursus in, arcu.

Methods: Pellentesque mauris ipsum, convallis in, hendrerit vel, ornare at, sapien.. Vivamus vitae leo vel urna molestie placerat. Aenean enim libero, accumsan et, posuere sit amet, congue ac, eros.. Vestibulum venenatis turpis sit amet mauris.. Aliquam ipsum lorem, consectetuer vitae, scelerisque sit amet, ultricies ac, risus. Vivamus et sapien nec metus faucibus luctus. Mauris dolor pede, fermentum tempus, auctor et, eleifend quis, mauris. Vestibulum nibh libero, feugiat eu, eleifend ac, rhoncus in, libero.

Results: Fusce mi pede, laoreet in, facilisis at, suscipit sed, magna. Nam nisl leo, venenatis eu, ornare ac, viverra id, lacus. Cras nisl ante, mattis in, placerat a, consectetuer ut, ligula. Donec sit amet libero a magna semper accumsan. Suspendisse quam leo, convallis a, tristique non, vulputate vel, ligula. In velit nisi, ultrices vitae, congue nec, venenatis sed, ipsum. Duis justo ipsum, placerat in, imperdiet vel, venenatis et, justo. Duis blandit metus sit amet nulla lacinia pharetra.

Conclusions: Maecenas mi dolor, ultricies sit amet, tincidunt nec, condimentum sed, libero. Nulla mauris ipsum, ornare sit amet, sagittis pellentesque, malesuada in, orci. Donec quam diam, fermentum et, consequat non, viverra sed, sem. Morbi nisl arcu, tincidunt ullamcorper, malesuada sit amet, gravida eget, sapien. Aenean id metus at lorem ultricies pharetra. Ut leo dolor, mollis vel, convallis quis, lacinia vitae, lacus. Sed vehicula lectus id dolor rhoncus feugiat. Suspendisse id leo nec nunc pulvinar suscipit.

Kľúčové slová: Etiam arcu

Vložený: January 23, 2013; Přijatý: April 17, 2013; Uverejnené online: May 3, 2013; Uverejnené: June 21, 2013 


Referencie

  1. Friedman M. Tomato glycoalkaloids: Role in the plant and in the diet. J Agric Food Chem 2002;50:5751-80. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  2. Schmidt B, Ribnicky DM, Poulev A, Logendra S, Cefalu WT, Raskin I. A natural history of botanical therapeutics. Metabolism 2008;57:S3-9. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  3. Friedman M, Fitch TE, Yokoyama WE. Lowering of plasma LDL cholesterol in hamsters by the tomato glycoalkaloid tomatine. Food Chem Toxicol 2000;38:549-53. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  4. Thorne HV, Clarke GF, Skuce R. The inactivation of herpes simplex virus by some Solanaceae glycoalkaloids. Antiviral Res 1985;5:335-43. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  5. Morrow WJW, Yang YW, Sheikh NA. Immunobiology of the tomatine adjuvant. Vaccine 2004;22:2380-4. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  6. Friedman M, McQuistan T, Hendricks JD, Pereira C, Bailey GS. Protective effect of dietary tomatine against dibenzo[a,l]pyrene (DBP)-induced liver and stomach tumors in rainbow trout. Mol Nutr Food Res 2007;51:1485-91. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  7. Lee KR, Kozukue N, Han JS, Park JH, Chang EY, Baek EJ, Chang JS, Friedman M. Glycoalkaloids and metabolites inhibit the growth of human colon (HT29) and liver (HepG2) cancer cells. J Agric Food Chem 2004;19:2832-9. Prejsť k pôvodnému zdroju...
  8. Friedman M, Levin CE. Tomatine-containing green tomato extracts inhibit growth of human breast, colon, liver, and stomach cancer cells. J Agric Food Chem 2009;57:5727-33. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  9. Chiu FL, Lin JK. Tomatidine inhibits iNOS and COX-2 through suppression of NF-kappaB and JNK pathways in LPS-stimulated mouse macrophages. FEBS Lett 2008;582:2407-12. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  10. Shih YW, Shieh J M, Wu PF, Lee YC, Chen YZ, Chiang TA. α-Tomatine inactivates PI3K/Akt and ERK signaling pathways in human lung adenocarcinoma A549 cells: effect on metastasis. Food Chem Toxicol 2009;47:1985-95. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  11. Liao DW, Wang L, Zhang XG, Liu MQ. Expression and significance of PTEN/PI3K signal transduction-related proteins in non-small cell lung cancer. Chin J Canc 2006; 25:1238-42.
  12. Itoh Y, Nagase H. Matrix metalloproteinases in cancer. Essays Biochem 2002;38,21-36. Prejsť na PubMed...
  13. Duffy MJ, Duggan C. The urokinase plasminogen activator system: A rich source of tumor markers for the individualised management of patients with cancer. Clin Biochem 2004;37:541-8. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  14. Lee ST, Wong PF, Cheah SC, Mustafa MR Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells.. PLoS ONE 2011;6:e18915. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  15. Shieh JM, Cheng TH, Shi MD, Wu PF, Chen Y, Ko SC, Shih YW. α-Tomatine suppresses invasion and migration of human non-small cell lung cancer NCI-H460 cells through inactivating FAK/PI3K/Akt signaling pathway and reducing binding activity of NF-κB. Cell Biochem Biophys 2011;60:297-310. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  16. Chao MW, Chen CH, Chang YL, Teng CM, Pan SL. α-Tomatine-Mediated Anti-Cancer Activity In Vitro and In Vivo through Cell Cycle- and Caspase-Independent Pathways. PLoS ONE 2012;9:e44093. Prejsť k pôvodnému zdroju...
  17. Kudelova J, Seifrtova M, Sucha L, Tomsik P, Havelek R, Rezacova M. Alpha-tomatine activates cell cycle checkpoints in the absence of DNA damage in human leukemic MOLT-4 cells. J Appl Biomed 2013;11:93-103. Prejsť k pôvodnému zdroju...
  18. Nishie K, Norred WP, Swain AP. Pharmacology and toxicology of chaconine and tomatine. Res Commun Chem Pathol Pharmacol 1975;12:657-68. Prejsť na PubMed...
  19. Awara WM, El-Sisi AE, El-Sayad ME, Goda AE. The potential role of cyclooxygenase-2 inhibitors in the treatment of experimentally-induced mammary tumour: does celecoxib enhance the anti-tumour activity of DOX? Pharmacol Res 2004;50:487-98. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  20. Klein HO, Toermer HJ, Christian E, Coerper C, Lennartz KJ, Akokan G. Experimental investigations on a sequential combination chemotherapy protocol. J Cancer Res Clin Oncol 1980;96:65-78. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  21. Mattern J, Kaufmann M, Wayss K, Volm M. Studies on the Drug Sensitivity of Short Term Cultivated Tumor Cell Suspensions. In: Dendy, PP,editor. Human Tumors in Short Term Culture, Academic Press, London (UK), New York (NY), San Francisco (CA); 1976. p 301.
  22. Tomsik P, Stoklasova A, Micuda S, Niang M, Suba P, Knizek J, Rezacova M. Evaluation of the antineoplastic activity of L-rhamnose in vitro. A comparison with 2-deoxyglucose. Acta Med (Hradec Kralove) 2008;51:113-9. Prejsť na PubMed...
  23. Pessina A, Brambilla P, Mocarelli P. Surface antigen on Ehrlich ascites tumor cells. Biomedicine 1980;33:105-9. Prejsť na PubMed...
  24. Segura JA, Barbero LG, Marquez J. Early tumor effect on splenic Th lymphocytes in mice. FEBS Lett 1997;414:1-6. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  25. Cespedes MV, Casanova I, Parreno M, Mangues R. Mouse models in oncogenesis and cancer therapy. Clin Transl Oncol 2006;8:318-29. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  26. Polin L, Corbett TH, Roberts BJ, Lawson AJ, Leopold III WR, White K, Kushner J, Hazeldine S, Moore R, Rake J, Horwitz JP. Transplantable Syngeneic Rodent Tumors. In: Teicher BA, editor. Tumor Models in Cancer Research, 2nd edn. Humana Press, Springer: New York (NY), Dordrecht (Netherlands), Heidelberg (Germany), London (UK); 2011. p 47
  27. Haque E, Baral R. Neem (Azadirachta indica) leaf preparation induces prophylactic growth inhibition of murine Ehrlich carcinoma in Swiss and C57BL/6 mice by activation of NK cells and NK-T cells. Immunobiology 2006;211:721-31. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  28. Israel M, Idriss JM, Koseki Y, Khetarpal VK. Comparative effects of adriamycin and DNA-non-binding analogues on DNA, RNA, and protein synthesis in vitro. Cancer Chemother Pharmacol 1987;20:277-84. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  29. Schaefer A, Boldt J, Westendorf J, Steinheider G, Marquardt H. Inhibition of amino acid uptake and incorporation into proteins in Friend erythroleukemia cells by the anthracycline antitumor antibiotic aclacinomycin A. Biochem Pharmacol 1988;37: 1377-82. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  30. Ebbehoj E, Langkjer ST. Comparison between different parameters of cell viability. In vitro studies in a human cervix cancercell line. J Exp Clin Cancer Res 1995;14:95-101.
  31. Lavie Y, Harel-Orbital T, Gaffield W, Liscovitch M. Inhibitory effect of steroidal alkaloids on drug transport and multidrug resistance in human cancer cells. Anticancer Res 2001;21:1189-94. Prejsť na PubMed...
  32. Keukens EA, de Vrije T; van den Boom C, de Waard P, Plasman HH, Thiel F, Chupin V, Jongen WM, de Kruijff B. Molecular basis of glycoalkaloid induced membrane disruption. Biochim Biophys Acta 1995;1240:216-28. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  33. Keukens EA, de Vrije T, Jansen LA, de Boer H, Janssen M, de Kroon AI, Jongen WM, de Kruijff B. Glycoalkaloids selectively permeabilize cholesterol containing biomembranes. Biochim Biophys Acta 1996;1279:243-50. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  34. Walker BW, Manhanke N, Stine KJ. Comparison of the interaction of tomatine with mixed monolayers containing phospholipid, egg sphingomyelin, and sterols. Biochim Biophys Acta 2008;1778:2244-57. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  35. Hartveit F. The growth of Ehrlich's ascites carcinoma in C3H mice and in mice of an unrelated closed colony. Splenomegaly following intraperitoneal transplantation. Br J Cancer 1966;20:825-30. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  36. Lala PK, Terrin M, Lind C, Kaizer L. Hemopoietic redistribution in tumor-bearing mice. Exp Hematol 1978;6:283-98. Prejsť na PubMed...
  37. Rivenson A, Schnelle V, Moroson H, Madden R, Herp A. Variable response of spleen to ehrlich's tumor according to the physical form (ascitic or solid) of the tumor. Experientia 1981;37:195-7. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  38. Queiroz ML, Valadares MC, Bincoletto C, Dieamant GC. Ehrlich ascites tumor as a tool in the development of compounds with immunomodulatory properties. Immunopharmacol Immunotoxicol 2004;26:511-25. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  39. Theologides A, Pegelow CH. Liver weight changes during distant growth of transplanted tumor. Proc Soc Exp Biol Med 1970;134:1104-8. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  40. Friedman M, Henika PR, Mackey BE. Feeding of potato, tomato and eggplant alkaloids affects food consumption and body and liver weights in mice. J Nutr 1996;126:989-9. Prejsť na PubMed...
  41. Dalvi RR. Comparative assessment of the effect of solanine administered orally and intraperitoneally on hepatic dysfunction in male rats. Jpn J Vet Sci (Nihon Juigaku Zasshi) 1985;47:657-9. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  42. Kathiriya A, Das K, Kumar EP, Mathai KB. Evaluation of antitumor and antioxidant activity of Oxalis Corniculata Linn. against ehrlich ascites carcinoma on mice. Iran J Cancer Prev 2010;3:157-65.
  43. Naveena, Bharath BK, Selvasubramanian. Antitumor activity of Aloe vera against Ehrlich ascitis carcinoma (EAC) in Swiss albino mice. Int J Pharm Bio Sci 2011;2:400-9.
  44. Wilson RW, Poley GH, de Eds F. Some pharmacologic and toxicologic properties of tomatine and its derivatives. Toxicol Appl Pharmacol 1961;3:39-48. Prejsť k pôvodnému zdroju... Prejsť na PubMed...
  45. Mimnaugh EG, Trush MA, Ginsburg E. The effects of adriamycin in vitro and in vivo on hepatic microsomal drug-metabolizing enzymes: Role of microsomal lipid peroxidation. Toxicol Appl Pharmacol 1981;61:313-25. Prejsť k pôvodnému zdroju... Prejsť na PubMed...